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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">smp</journal-id><journal-title-group><journal-title xml:lang="ru">Скорая медицинская помощь</journal-title><trans-title-group xml:lang="en"><trans-title>EMERGENCY MEDICAL CARE</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6716</issn><publisher><publisher-name>Northwest State Medical University named after II Mechnikov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/2072-6716-2014-15-2-65-69</article-id><article-id custom-type="elpub" pub-id-type="custom">smp-13</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СКОРАЯ МЕДИЦИНСКАЯ ПОМОЩЬ В СТАЦИОНАРЕ INTRAHOSPITAL EMERGENCY MEDICAL CARE</subject></subj-group></article-categories><title-group><article-title>ПРОГНОСТИЧЕСКОЕ ЗНАЧЕНИЕ СОДЕРЖАНИЯ ИЛ-6, ИЛ-10И РАИЛ ДЛЯ ДИАГНОСТИКИ РАЗВИТИЯ СЕПСИСА И ТЯЖЕЛОГО СЕПСИСА У ПАЦИЕНТОВ С СОЧЕТАННОЙ ТРАВМОЙ</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малышев</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Malyshev</surname><given-names>M. E.</given-names></name></name-alternatives><email xlink:type="simple">malyshev1972@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пивоварова</surname><given-names>Л. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Pivovarova</surname><given-names>L. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Osipova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арискина</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Ariskina</surname><given-names>O. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хабирова</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Habirova</surname><given-names>T. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильина</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilyina</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский институт скорой помощи им. И. И. Джанелидзе, Санкт-Петербург, Россия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Dzhanelidze Research Institute of Emergency Care, St.-Petersburg, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2016</year></pub-date><volume>15</volume><issue>2</issue><fpage>65</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Малышев М.Е., Пивоварова Л.П., Осипова И.В., Арискина О.Б., Хабирова Т.Г., Ильина В.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Малышев М.Е., Пивоварова Л.П., Осипова И.В., Арискина О.Б., Хабирова Т.Г., Ильина В.А.</copyright-holder><copyright-holder xml:lang="en">Malyshev M.E., Pivovarova L.P., Osipova I.V., Ariskina O.B., Habirova T.G., Ilyina V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://smp.spb.ru/jour/article/view/13">https://smp.spb.ru/jour/article/view/13</self-uri><abstract><p>Исследовали содержание цитокинов у 88 пациентов с сочетанной механической травмой, сопро- вождаемой развитием шока, с последующим развитием сепсиса и тяжелого сепсиса, чтобы опре- делить надежные лабораторные критерии диагностики гнойных осложнений на основе показателей медиаторов воспаления в период ранних проявлений травматической болезни. Содержание ИЛ-6, ИЛ-10, РАИЛ в сыворотке крови и уровень кортизола в крови при поступлении в стационар могут служить достоверными прогностическими факторами риска развития сепсиса и тяжелого сепсиса при сочетанной травме.</p></abstract><kwd-group xml:lang="ru"><kwd>сочетанная травма</kwd><kwd>сепсис</kwd><kwd>тяжелый сепсис</kwd><kwd>цитокины</kwd><kwd>combined trauma</kwd><kwd>sepsis</kwd><kwd>severe sepsis</kwd><kwd>cytokines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bone R. C. Toward an epidemiology and natural history of SIRS (systemic inflammatory response syndrome) // JAMA.- 1992.- Vol. 268, № 24.- P. 3452-3455</mixed-citation><mixed-citation xml:lang="en">Bone R. C. 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