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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">smp</journal-id><journal-title-group><journal-title xml:lang="ru">Скорая медицинская помощь</journal-title><trans-title-group xml:lang="en"><trans-title>EMERGENCY MEDICAL CARE</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6716</issn><publisher><publisher-name>Northwest State Medical University named after II Mechnikov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/2072-6716-2017-18-1-64-68</article-id><article-id custom-type="elpub" pub-id-type="custom">smp-191</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTICLES</subject></subj-group></article-categories><title-group><article-title>СКОРАЯ МЕДИЦИНСКАЯ ПОМОЩЬ ПРИ ОТРАВЛЕНИИ СПАЙСАМИ</article-title><trans-title-group xml:lang="en"><trans-title>EMERGENCY MEDICAL CARE IN CASE OF SPICE POISONINGS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афанасьев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Afanasiev</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Афанасьев Василий Владимирович.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St.  Petersburg</p></bio><email xlink:type="simple">sobaka_liza@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St.  Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бузанов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Buzanov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St.  Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Великова</surname><given-names>В. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Velicova</surname><given-names>V. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St.  Petersburg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет имени И. И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University named after I. I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт токсикологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Toxicology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>10</day><month>02</month><year>2017</year></pub-date><volume>18</volume><issue>1</issue><fpage>64</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Афанасьев В.В., Петрова Н.В., Бузанов Д.В., Великова В.Д., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Афанасьев В.В., Петрова Н.В., Бузанов Д.В., Великова В.Д.</copyright-holder><copyright-holder xml:lang="en">Afanasiev V.V., Petrova N.V., Buzanov D.V., Velicova V.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://smp.spb.ru/jour/article/view/191">https://smp.spb.ru/jour/article/view/191</self-uri><abstract><p>На  современном этапе  отравления спайсами занимают ведущее место в структуре острых отравлений  наркогенами. Рассмотрены виды  действия природных и синтетических спайсов и их комбинаций  с галлюциногенами-стимуляторами и антидепрессантами. Показаны клинические варианты развития  отравления и особенности адренергического синдрома, возникающего при нем. Представлены результаты исследования нового фармакологического подхода с применением холин и аденозинергических препаратов, позволяющих снизить повреждающее действие дизайнерских спайсов на организм  человека.</p></abstract><trans-abstract xml:lang="en"><p>Spice  overdose became a leading type  of poisonings among illicit  designer drugs.  The particularities of natural  and  synthetic spices  with  the  hallucinogenic action are  discussed with  determination of specificity in  adrenergic  toxsyndrome.  Administration of  cholinergic and  adenosinic  medications ameliorate the consequences of psychosis and  adrenergic toxsyndrome, and  seemed to be the  novel  approach in treatment of spice  poisonings.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>спайсы</kwd><kwd>психоз</kwd><kwd>адренергический токсиндром</kwd><kwd>холинергические и аденозинергические средства</kwd></kwd-group><kwd-group xml:lang="en"><kwd>spice</kwd><kwd>psychosis</kwd><kwd>adrenergic toxsyndrome</kwd><kwd>cholinergic and adenosinic medications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Чурюканов М. 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