smpСкорая медицинская помощьEMERGENCY MEDICAL CARE2072-6716Northwest State Medical University named after II Mechnikov10.24884/2072-6716-2017-18-2-45-49smp-207Research ArticleОБЗОРЫREVIEWSАНАФИЛАКТИЧЕСКИЙ ШОК— СТАРОЕ И НОВОЕ В ТАКТИКЕ ЛЕЧЕНИЯANAPHYLACTIC SHOCK— THE OLD AND THE NEW IN THE TACTICS OF TREATMENTБулачТ. П.BulachT. P.

Санкт-Петербург

Контакт: Булач Тамара Петровна

mtp007@yandex.ruМарусановВ. Е.MarusanovV. E.СемкичевВ. А.SemkichevV. A.Северо-Западный государственный медицинский университет им. И.И. МечниковаРоссияNorth-Western State Medical University named after I. I. MechnikovRussian Federation2017171020171824549Copyright © Булач Т.П., Марусанов В.Е., Семкичев В.А., 20172017Булач Т.П., Марусанов В.Е., Семкичев В.А.Bulach T.P., Marusanov V.E., Semkichev V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://smp.spb.ru/jour/article/view/207

В последние годы отмечается увеличение числа аллергических заболеваний, наиболее тяжелым из которых является анафилактический шок. Обзор отражает международный опыт лечения анафилактического шока и направлен на то, чтобы определить верную тактику ведения пациента с этой тяжелой патологией. 

Allergy is an adverse immune system reaction to a particular allergen. In recent years there has been an increase in the number of allergic diseases, the most severe of which is anaphylactic shock. Our review reflects the international experience of the strategy of treating anaphylactic shock and is aimed at determining the correct tactics of managing a patient with this severe pathology. 

скорая медицинская помощьанафилактический шокадреналининфузионная терапияеmergency medical servicesanaphylactic shockepinephrineinfusion therapyReferencesКовальчук Е.Ю. Клинические рекомендации (протокол) по оказанию скорой медицинской помощи при анафилактическом шоке. РОСМП, от 23 января 2014, г. Казань. Femb.ru. 2014. [Kovalchuk E. Yu. Klinicheskie rekomendacii (protokol) po okazaniyu skoroj medicinskoj pomoshhi pri anafilakticheskom shoke. ROSMP, ot 23 yanvarya 2014, g. Kazan. Femb.ru. 2014. (In Russ.)].Ковальчук Е.Ю. Клинические рекомендации (протокол) по оказанию скорой медицинской помощи при анафилактическом шоке. РОСМП, от 23 января 2014, г. Казань. Femb.ru. 2014. [Kovalchuk E. Yu. Klinicheskie rekomendacii (protokol) po okazaniyu skoroj medicinskoj pomoshhi pri anafilakticheskom shoke. ROSMP, ot 23 yanvarya 2014, g. Kazan. Femb.ru. 2014. (In Russ.)].Commins S.P. Outpatient Emergencies: Anaphylaxis. Med Clin North, 2017, Vol. 101 (3), pp. 521–536. doi: 10.1016/j.mcna.2016.12.003.Commins S.P. Outpatient Emergencies: Anaphylaxis. Med Clin North, 2017, Vol. 101 (3), pp. 521–536. doi: 10.1016/j.mcna.2016.12.003.Korosec P., Turner P.J., Silar M. et al. Basophils. high-affinity IgE receptors and CCL2 in human anaphylaxis. J. Allergy Clin. Immunol., 2017, Mar. 22, pii: S0091–6749(17)30423–2. doi: 10.1016/j.jaci.2016.12.989.Korosec P., Turner P.J., Silar M. et al. Basophils. high-affinity IgE receptors and CCL2 in human anaphylaxis. J. Allergy Clin. Immunol., 2017, Mar. 22, pii: S0091–6749(17)30423–2. doi: 10.1016/j.jaci.2016.12.989.Cmorej P.C., Nesvadba M. et al. Management of acute anaphylaxis in clinical practice in the context of the guidelines. Epidemiol Miсrobiol Imunol., 2017, Vol. 66 (1), рр. 30–38.Cmorej P.C., Nesvadba M. et al. Management of acute anaphylaxis in clinical practice in the context of the guidelines. Epidemiol Miсrobiol Imunol., 2017, Vol. 66 (1), рр. 30–38.Harper N. J., Dixon T., Dugué P. et al. Suspected anaphylactic reactions associated with anaesthesia. Anaesthesia, 2009, Vol. 64 (2), рр. 199–211. doi: 10.1111/j.Harper N. J., Dixon T., Dugué P. et al. Suspected anaphylactic reactions associated with anaesthesia. Anaesthesia, 2009, Vol. 64 (2), рр. 199–211. doi: 10.1111/j.Tang M.L., Mullins R.J.. Food allergy: is prevalence increasing? Intern Med. J., 2017, Vol. 47 (3), рр. 256–261. doi: 10.1111/imj.13362.Tang M.L., Mullins R.J.. Food allergy: is prevalence increasing? Intern Med. J., 2017, Vol. 47 (3), рр. 256–261. doi: 10.1111/imj.13362.Yanagida N., Sato S., Asaumi T. et al. Risk Factors for Severe Reactions during Double-Blind Placebo-Controlled Food Challenges. Int. Arch. Allergy Immunol., 2017, Vol. 172 (3), рр. 173–182. doi: 10.1159/000458724.Yanagida N., Sato S., Asaumi T. et al. Risk Factors for Severe Reactions during Double-Blind Placebo-Controlled Food Challenges. Int. Arch. Allergy Immunol., 2017, Vol. 172 (3), рр. 173–182. doi: 10.1159/000458724.Gikas A., Lazaros G., Kontou-Fili K. Acute ST-segment elevation myocardial infarction after amoxycillininduced anaphylactic shock in a young adult with normal coronary arteries: a case report. BMC Cardiovasc Disord., 2005, Vol. 5 (1), рр. 6.Gikas A., Lazaros G., Kontou-Fili K. Acute ST-segment elevation myocardial infarction after amoxycillininduced anaphylactic shock in a young adult with normal coronary arteries: a case report. BMC Cardiovasc Disord., 2005, Vol. 5 (1), рр. 6.Schwartz LB. Diagnostic value of tryptase in anaphylaxis and mastocytosis. Immunol Allergy Clin. North Am., 2006, Vol. 26 (3), рр. 451–463.Schwartz LB. Diagnostic value of tryptase in anaphylaxis and mastocytosis. Immunol Allergy Clin. North Am., 2006, Vol. 26 (3), рр. 451–463.Sheikh A., Shehata Y.A., Brown S.G. et al. Adrenaline (epinephrine) for the treatment of anaphylaxis with and without shock. Cochrane Database Syst Rev. 2008, Vol. 4, рр. CD006312. doi: 10.1002/14651858.CD006312.pub2.Sheikh A., Shehata Y.A., Brown S.G. et al. Adrenaline (epinephrine) for the treatment of anaphylaxis with and without shock. Cochrane Database Syst Rev. 2008, Vol. 4, рр. CD006312. doi: 10.1002/14651858.CD006312.pub2.Campbell R.L., Bellolio M.F., Knutson B.D. et al. Epinephrine in anaphylaxis: higher risk of cardiovascular complications and overdose after administration of intravenous bolus epinephrine compared with intramuscular epinephrine. J. Allergy Clin. Immunol. Pract., 2015, Vol. 3 (1), рр. 76–80. doi: 10.1016Campbell R.L., Bellolio M.F., Knutson B.D. et al. Epinephrine in anaphylaxis: higher risk of cardiovascular complications and overdose after administration of intravenous bolus epinephrine compared with intramuscular epinephrine. J. Allergy Clin. Immunol. Pract., 2015, Vol. 3 (1), рр. 76–80. doi: 10.1016Simons F.E., Simons K. J. Epinephrine absorption in adults: intramuscular versus subcutaneous injection. J. Allergy Clin. Immunol., 2001, Vol. 108 (5), рр. 871–873.Simons F.E., Simons K. J. Epinephrine absorption in adults: intramuscular versus subcutaneous injection. J. Allergy Clin. Immunol., 2001, Vol. 108 (5), рр. 871–873.Singletary E.M., Charlton N.P., Epstein J.L. et al. Part 15: First Aid 2015 American Heart Association and American Red Cross Guidelines Update for First Aid. Circulation, 2015, Nov. 3, рр. 574–589. doi: 10.1161/CIR.0000000000000269.Singletary E.M., Charlton N.P., Epstein J.L. et al. Part 15: First Aid 2015 American Heart Association and American Red Cross Guidelines Update for First Aid. Circulation, 2015, Nov. 3, рр. 574–589. doi: 10.1161/CIR.0000000000000269.Brasted I. D., Dailey M.W. Basic Life Support Access to Injectable Epinephrine across the United States. Prehosp. Emerg. Care, 2017, Vol. 24, рр. 1–6. doi: 10.1080/10903127.2017.1294224.Brasted I. D., Dailey M.W. Basic Life Support Access to Injectable Epinephrine across the United States. Prehosp. Emerg. Care, 2017, Vol. 24, рр. 1–6. doi: 10.1080/10903127.2017.1294224.Schummer C., Wirsing M., Schummer W. The pivotal role of vasopressin in refractory anaphylactic shock. Anesth Analg., 2008, Vol. 107 (2). рр. 620–624. doi: 10.1213Schummer C., Wirsing M., Schummer W. The pivotal role of vasopressin in refractory anaphylactic shock. Anesth Analg., 2008, Vol. 107 (2). рр. 620–624. doi: 10.1213Thomas M., Crawford I. Best evidence topic report. Glucagon infusion in refractory anaphylactic shock in patients on beta-blockers. Emerg. Med. J., 2005, Vol. 22 (4), рр. 272–273. doi: 10.1136/emj.2005.023507.Thomas M., Crawford I. Best evidence topic report. Glucagon infusion in refractory anaphylactic shock in patients on beta-blockers. Emerg. Med. J., 2005, Vol. 22 (4), рр. 272–273. doi: 10.1136/emj.2005.023507.Sheikh A., Ten Broek V., Brown S. G., Simons F.E. H1-antihistamines for the treatment of anaphylaxis: Cochrane systematic review. Allergy, 2007, Vol. 62 (8), рр. 830–837.Sheikh A., Ten Broek V., Brown S. G., Simons F.E. H1-antihistamines for the treatment of anaphylaxis: Cochrane systematic review. Allergy, 2007, Vol. 62 (8), рр. 830–837.Choo K.J., Simons F.E., Sheikh A. Glucocorticoids for the treatment of anaphylaxis. Evid. Based Child Health, 2013, Vol. 8 (4), рр. 1276–1294. doi: 10.1002/ebch.1925.Choo K.J., Simons F.E., Sheikh A. Glucocorticoids for the treatment of anaphylaxis. Evid. Based Child Health, 2013, Vol. 8 (4), рр. 1276–1294. doi: 10.1002/ebch.1925.

The authors declare that there are no conflicts of interest present.