smpСкорая медицинская помощьEMERGENCY MEDICAL CARE2072-6716Northwest State Medical University named after II Mechnikov10.24884/2072-6716-2024-25-3-92-97smp-867Research ArticleПЕДИАТРИЯPEDIATRICSЭффективность глюкокортикостероидов при интенсивной терапии острого обструктивного ларингита у детей. ОбзорЕfficacy of glucocorticoids in intensive treatment of acute obstructive laryngitis in children: a reviewБыковЮ. В.BykovYu. V.

Быков Юрий Витальевич — кандидат медицинских наук, доцент кафедры анестезиологии и реаниматологии с курсом ДПО 

355017, Ставрополь, ул. Мира, д. 310

Bykov Yuri Vitalevich

Stavropol

 

yubykov@gmail.comОбединА. Н.ОbedinA. N.

Обедин Александр Николаевич — доктор медицинских наук, заведующий кафедрой анестезиологии и реаниматологии с курсом ДПО 

355017, Ставрополь, ул. Мира, д. 310

Аlexander N. Оbedin

Stavropol

volander@mail.ruЗинченкоО. B.ZinchenkoО. V.

Зинченко Олег Васильевич — кандидат медицинских наук, доцент кафедры анестезиологии и реаниматологии с курсом ДПО 

355017, Ставрополь, ул. Мира, д. 310

Оleg V. Zinchenko

Stavropol

regionar2008@yandex.ruЯцукИ. В.YatsukI. V.

Яцук Иван Викторович — кандидат медицинских наук, доцент кафедры анестезиологии и реаниматологии с курсом ДПО

355017, Ставрополь, ул. Мира, д. 310

Ivan V. Yatsuk

Stavropol

yatsukiv@gmail.comСтавропольский государственный медицинский университетРоссияStavropol State Medical Universityl State Medical UniversityRussian FederationСтавропольский государственный медицинский университетРоссияStavropol State Medical UniversityRussian Federation2024130220252539297Copyright © Быков Ю.В., Обедин А.Н., Зинченко О.B., Яцук И.В., 20252025Быков Ю.В., Обедин А.Н., Зинченко О.B., Яцук И.В.Bykov Y.V., Оbedin A.N., Zinchenko О.V., Yatsuk I.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://smp.spb.ru/jour/article/view/867Цель

Цель. Проанализировать данные зарубежной и отечественной периодической литературы по аспектам назначения глюкокортикостериодов (ГКС) при остром обструктивном ларингите (ООЛ) в детском возрасте.

Материалы и методы

Материалы и методы. Рассмотрено 33 зарубежных и отечественных источника по изучаемой проблеме, в том числе 15 источников за последние 5 лет.

Результаты

Результаты. По данным разных авторов рассмотрены механизмы действия ГКС, проведено обоснование их терапевтической эффективности в качестве препаратов выбора при любой степени тяжести ООЛ как на догоспитальном, там и на госпитальном этапе. Выполнена сравнительная характеристика различных неингаляционных и ингаляционных ГКС (дексаметазон, преднизолон, будесонид, беклометазон, флутиказон) при интенсивной терапии ООЛ в педиатрической практике.

Заключение

Заключение. Целесообразно назначение ГКС при ООБ у детей. Лучшее понимание особенностей назначения ГКС у детей с ООЛ должно повысить качество неотложной помощи при данном патологическом состоянии.

Goal

Goal. To analyze the data of foreign and domestic periodical literature on the aspects of the appointment of glucocorticosteroids (GCs) in acute obstructive laryngitis (АOL) in childhood.

Materials and methods

Materials and methods. 33 foreign and domestic sources on the studied problem were considered, including 15 sources over the past 5 years.

Results

Results. According to different authors, the following are considered the mechanisms of action of GC drugs, this paper provides evidence of their therapeutic efficacy, justifying their use as treatment of choice in AOL of any severity grade, in the prehospital as well as hospital settings. The characteristics of a range of different GCs (dexamethasone, prednisolone, budesonide, beclometasone, fluticasone) administered through inhalation and other routes are compared in regard to their use in intensive treatment of AOL in pediatric  practice.

Conclusion

Conclusion. It is advisable to prescribe GCs for AOL in children. A better understanding of the particulars of use of GCs in children with AOL should improve the quality of intensive care in this pathology.

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The authors declare that there are no conflicts of interest present.