Features of blood clotting system in girls with abnormal uterine bleeding of the puberty period
https://doi.org/10.24884/2072-6716-2021-22-4-70-75
Abstract
Objective: to evaluate the blood clotting system based on laboratory data in adolescent girls with uterine bleeding of the puberty period (MCPP). The study included 151 girls from 9 to 17 years old, of which 101 patients with MСPP and 50 patients with somatic pathology who do not suffer from MСPP. All patients underwent laboratory tests of blood coagulation parameters. The results of the study revealed lower values of the prothrombin index (PTI) and a tendency of compensatory increase in fibrinogen levels with a decrease in Duke bleeding time in the period of acute uterine bleeding in patients of the main group. In patients with MСPP, the threshold values of the blood clotting system parameters for the occurrence of uterine bleeding were determined, these are the level of PTI≤71.25%, fibrinogen ≤4.45 g/l, bleeding time according to Duque <2.38 min (p<0,05 according to the criterion χ2). The analysis of the obtained results indicates the presence of signs of insufficiency of the vascular-platelet hemostasis link in girls with MCPP.
About the Authors
A. V. Emelyanova
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Anna V. Emelyanova
St. Petersburg
V. M. Shaytor
North-Western State Medical University named after I. I. Mechnicov
Russian Federation
Russian Federation
Valentina M. Shaytor
St. Petersburg
M. O. Revnova
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Maria O. Revnova
St. Petersburg
D. I. Shaytor
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Danila I. Shaytor
St. Petersburg
E. Yu. Airapetian
Clinic «Osnova»
Russian Federation
Russian Federation
Elisa Yu. Airapetian
St. Petersburg
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Review
For citations:
Emelyanova A.V., Shaytor V.M., Revnova M.O., Shaytor D.I., Airapetian E.Yu. Features of blood clotting system in girls with abnormal uterine bleeding of the puberty period. EMERGENCY MEDICAL CARE. 2021;22(4):70-75. (In Russ.) https://doi.org/10.24884/2072-6716-2021-22-4-70-75
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