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Acute methanol poisoning

https://doi.org/10.24884/2072-6716-2024-25-2-75-81

Abstract

According to the state report «On the state of sanitary and epidemiological welfare of the population in the Russian Federation in 2021», the indicator of acute poisoning with alcohol- containing products amounted to 21.19 cases per 100 thousand population [1]. The purpose of the study: analytical toxicological analysis, features of diagnosis and intensive care of patients hospitalized with acute methanol poisoning in the toxicological center of the metropolis. Materials and methods of research. The medical documents of 46 patients admitted to the Acute Poisoning Center were analyzed GBU St. Petersburg Research Institute of Joint Venture named after I. I. Janelidze in 2019–2022 with a diagnosis of «Acute methanol poisoning». Category ICD-10: T51.1. A statistical and chemical- toxicological study was conducted upon admission of patients to the hospital and in dynamics after intensive care. The results of the study. According to the data of the Central Research Center of the St. Petersburg Research Institute of Joint Venture named after I. I. Janelidze, the number of patients with acute methyl alcohol poisoning was: 2019, 10 patients were admitted (of which 3 patients died); 2020, 11 patients (3 died); 2021, 12 patients out of 15 patients died; 2022, out of 10 patients with acute poisoning 7 patients died with methanol. All admitted patients with acute methyl alcohol poisoning were in critical condition with severe disorders of vital organs. Conclusion: methanol poisoning occupies one of the leading places among acute poisoning of chemical etiology both in frequency and in the number of adverse outcomes. They are characterized by severe medical, social and economic consequences.

About the Authors

R. A. Narzikulov
St. Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine
Russian Federation

Rustam A. Narzikulov

St. Petersburg



A. N. Lodyagin
St. Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine
Russian Federation

Alexey N. Lodyagin

St. Petersburg



B. V. Batotsyrenov
St. Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine
Russian Federation

Bair V. Batotsyrenov

St. Petersburg



O. A. Kuznetsov
St. Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine
Russian Federation

Oleg A. Kuznetsov

St. Petersburg



References

1. On the state of sanitary and epidemiological welfare of the population in the Russian Federation in 2021: State Report. Moscow: Federal Service for Supervision of Consumer Rights Protection and Human Well-being, 2022. 368 р. (In Russ.).

2. Luzhnikov E. A. Medical toxicology: National Guidelines. Moscow: Publishing house GEOTAR-Media, 2014. 928 p. (In Russ.).

3. Erokhin V. N., Narzikulov R. A., Shilov V. V. Toxic technical liquids. The mechanism of toxic action, the main manifestations of the toxic process, the principles of medical care. St. Petersburg: Publishing house of I. I. Mechnikov NWSMU, 2018. 63 p. (In Russ.).

4. Hoffman R., Nelson L., Howland M.-E., Lewin N., Flomenbaum N., Goldfrank L. Emergency medical care for poisoning. Moscow: Publishing house Practice, 2010. 1440 p. (In Russ.).

5. Luzhnikov E. A., Goldfarb Yu.S., Badalyan A. V. Detoxification therapy of acute poisoning at the present stage. Toxicological Bulletin, 2014, No. 3 (126), pp. 9–17 (In Russ.).

6. A method for measuring the mass concentration of low molecular weight alcohols and acetone in aqueous solutions, blood and urine. MNPC of Narcology of DM and Laboratory Equipment LLC, Moscow, 2016, certified by VNIIMS, certificate of certification of measurement methodology No. 205–26/RA. RU.311787–2016/2017 dated 03/20/2017, registered with the Federal Information Fund for Ensuring the Uniformity of Measurements (In Russ.).

7. The method of measuring the mass concentration of ethanol in the blood by the gas chromatographic method. The Ministry of Health of the Republic of Buryatia GAU «Republican Narcological Dispensary», Ulan- Ude, certified by VNIIMS, certificate of attestation No. 01.00225/205–34–14 dated 10/15/2014, registered with the Federal Information Fund for Ensuring the Uniformity of Measurements under the number FR.1.31.2014.19160 (In Russ.).

8. The report of the Department of Acute Poisoning of the GBU St. Petersburg Research Institute of SP named after I. I. Dzhanelidze for 2019 (Appendix No. 6 to the order of the Ministry of Health of the Russian Federation dated January 8, 2002 No. 9, Form No. 64, approved by Order of the Ministry of Health of the Russian Federation dated January 8, 2002 No. 9 (In Russ.).

9. The report of the Department of Acute Poisoning of the St. Petersburg State Medical University of the I. I. Janelidze Research Institute for 2020 (Appendix No. 6k to the Order of the Ministry of Health of the Russian Federation No. 9 dated January 8, 2002 No. 9, Form No. 64, approved by Order of the Ministry of Health of the Russian Federation dated January 8, 2002 No. 9 (In Russ.).

10. The report of the Department of Acute Poisoning of the GBU St. Petersburg Research Institute of Joint Venture named after I. I. Dzhanelidze for 2021 (Appendix No. 6 to the order of the Ministry of Health of the Russian Federation dated January 8, 2002 No. 9, Form No. 64, approved by Order of the Ministry of Health of the Russian Federation dated January 8, 2002 No. 9 (In Russ.).

11. The report of the Department of Acute Poisoning of the GBU St. Petersburg Research Institute of Joint Venture named after I. I. Dzhanelidze for 2022 (Appendix No. 6 to the order of the Ministry of Health of the Russian Federation dated January 8, 2002 No. 9, Form No. 64, approved by Order of the Ministry of Health of the Russian Federation dated January 8, 2002 No. 9 (In Russ.).

12. Emergency medical care in case of poisoning. St. Petersburg, 2012.1440 р. (In Russ.).

13. Management of critical medicine 7th edition/ under the direction of G.- L. Vincent. Per. with English. under science. red. Well.V. Grigoryeva: in 2 t. SPb.: Publishing house Human, 2019, Vol. 1, рр. 951–958 (In Russ.).

14. Brent J., Burkhart K., Dargan P., Hatten B., Megarbane B., Palmer R., White J. Critical Care Toxicology. Springer International Publishing AG 2017. https://doi.org/10.1007/978–3–319–17900–1.

15. Order of the Ministry of Health of the Russian Federation dated 05/10/2017 No. 203n «On approval of criteria for assessing the quality of medical care» (In Russ.).

16. Roberts D. M. et al. Recommendations for the Role of Extracorporeal Treatments in the Management of Acute Methanol Poisoning: A Systematic Review and Consensus Statement // Critical Care Medicine. 2015. Vol. 43, No. 2. Р. 461–472.

17. Ford Marsha D. et al. Clinical Toxicology. 1st ed. W. B. Saunders Company, 2001. 1138 p.

18. Brent J., Burkhart K., Dargan P., Hatten B., Megarbane B., Palmer R., White J. Critical Care Toxicology. Springer International Publishing AG 2017. https://doi.org/10.1007/978–3–319–17900–1.


Review

For citations:


Narzikulov R.A., Lodyagin A.N., Batotsyrenov B.V., Kuznetsov O.A. Acute methanol poisoning. EMERGENCY MEDICAL CARE. 2024;25(2):75-81. (In Russ.) https://doi.org/10.24884/2072-6716-2024-25-2-75-81

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