Influence of discharge time after coronary artery stenting on the incidence of restenosis and exacerbations of ischemic heart disease
https://doi.org/10.24884/2072-6716-2025-26-2-70-77
Abstract
Goal. To identify the significance of the timing of discharge of patients from the hospital after percutaneous coronary angioplasty on the incidence of restenosis and ischemic events. Materials and methods of research. We analyzed archival histories from 2021 to 2023; during this period, 1347 coronary artery stentings were performed; during the same period, 176 (13.1%) patients were re-hospitalized. Thus, the study included 176 patients: 111 (63.1%) men and 65 (36.9%) women. Results. The study showed that out of176 cases of complications, in the group with early discharge on days 1–3, there were initially 27.5% more of them, acute myocardial infarction (AMI) was observed more often by 25% (p<0.05), and hospital mortality from AMI, by 33.3% (p<0.05) than in patients with discharge of 4 days or more. Conclusions. Our non-randomized prospective study showed that early discharge from the hospital on the 1–3 day after stenting leads to the development of an adverse emergency event in patients with coronary heart disease. Acute myocardial infarction developed 25% (p<0.05) more often, and hospital mortality from acute myocardial infarction by 33.3% (p<0.05) than in patients with discharge on the 4th or later day.
About the Authors
A. A. AbdullaevRussian Federation
Aligadzhi A. Abdullaev
Makhachkala
R. G. Khabchabov
Russian Federation
Rustam G. Khabchabov
Makhachkala
E. R. Makhmudova
Russian Federation
Elmira R. Makhmudova
Makhachkala
R. M. Gafurova
Russian Federation
Raziyat M. Gafurova
Makhachkala
U. A. Islamova
Russian Federation
Ummet A. Islamova
Makhachkala
A. A. Anatova
Russian Federation
Aminat A. Anatova
Makhachkala
M. A. Dzhanbulatov
Russian Federation
Murat A. Dzhanbulatov
Makhachkala
References
1. Gratsiansky N.A. Antiplatelet therapy for coronary heart disease. Some problems and achievements. Atherothrombosis, 2019, Vol. 1, No. 4, рр. 2–17 (In Russ.). https://doi:10.15829/1560-4071-2021-4449.
2. Alekyan B.G., Grigoryan A.M., Staferov A.V., Karapetyan N.G. X-ray endovascular diagnosis and treatment of heart and vascular diseases in the Russian Federation. Endovascular surgery, 2018, Vol. 5, No. 2, рр. 93–240 (In Russ.). https://doi.10.24183/2409–4080–2018–5–2–93240.
3. Verdoia M., Kedhi E., Suryapranata H., Galasso G., Dudek D., De Luca G. Poly (l-lactic acid) bioresorbable scaffolds versus metallic drug-eluting stents for the treatment of coronary artery disease: A meta-analysis of 11 randomized trials // Catheter Cardiovasc Interv. 2020. Vol. 96, No. 4. Р. 813–824. https://doi.org/10.1002/ccd.28594.
4. Ioseliani D. G., Asadov D. A., Fomenko V. V., Azarov A.V., Semitko S.P. Five-year result of implantation of bioabsorbable stents Absorb using the bifurcation stenting technique. Cardiovascular Therapy and Prevention, 2021, Vol. 20, No. 4, рр. 28–64 (In Russ.). https://doi.org/10.15829/1728–8800–2021–2864.
5. Chun Shing Kwok, Malcolm Bell, H. Vernon Anderson, Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States // J. Am. Coll Cardiol. Intv. 2018. Vol. 11, No. 14. Р. 1354–1364. https://doi: 10.1016/j.jcin.2018.03.049.
6. Smits P.C., Chang C.C., Chevalier B., West N.E.J., Gori T., Barbato E. Bioresorbable vascular scaffold versus metallic drug-eluting stent in patients at high risk of restenosis: the COMPARE-ABSORB randomized clinical trial // EuroIntervention. 2020. Vol. 16, No. 8. Р. 645–653. https://doi.org/10.4244/EIJ-D-19–01079.
7. Kraak R. P., Tijssen R. Y.G., van Dongen I. M., Elias J., Hofma S. H., van der Schaaf R. J. Outcomes of bioresorbable vascular scaffolds versus everolimus-eluting stents by coronary complexity: a sub-analysis of the AIDA trial // EuroIntervention. 2020. Vol. 16, No. 11. Р. 904–912. https://doi.org/10.4244/EIJ-D-18–00884.
8. Ortega-Paz L., Brugaletta S., Sabaté M. Impact of PSP Technique on Clinical Outcomes Following Bioresorbable Scaffolds Implantation // J. Clin. Med. 2018. Vol. 7, No. 2. Р. 27–39. https://doi.org/10.3390/jcm7020027.
9. Keh Y.S., Yap J., Yeo K. K., Koh T. H., Eeckhout E. Clinical Outcomes of Bioresorbable Scaffold in Coronary Artery Disease: A Systematic Literature Review // J. Interv Cardiol. 2018. Vol. 29, No. 1. Р. 57–69. https://doi.org/10.1111/joic.12260.
10. Badour S. A., Dimitrova K. R., Kanei Y., Tranbaugh R. F., Hajjar M. M., Kabour A. et al. First and second generation DESs reduce diabetes adverse effect on mortality and re-intervention in multivessel coronary disease: 9-Year analysis // Cardiovascular Revascularization Medicine. 2017. Vol. 18, No. 4. Р. 265–273. https://doi.org/10.1016/j.carrev.2017.01.012.
11. Mangione F. M., Biering-Sørensen T., Nochioka K., Jatene T., Silvestre O. M., Hansen K.W. et al. Second generation drug-eluting stents versus bare-metal stents for percutaneous coronary intervention of the proximal left anterior descending artery: An analysis of the BASKET-PROVE I and II trials // Catheterization and Cardiovascular Interventions. 2018. Vol. 91, No. 5. Р. 867–873. https://doi.org/10.1002/ccd.27200
12. Zandvoort L.J.C., Bommel R.J., Masdjedi K., Tovar Forero M.N., Lemmert M.M., Wilschut J. et al. Long-term outcome in patients treated with first-versus second-generation drug-eluting stents for the treatment of unprotected left main coronary artery stenosis // Catheterization and Cardiovascular Interventions. 2019. Vol. 2, No. 8. Р. 38–47. https://doi.org/10.1002/ccd.28387.
Review
For citations:
Abdullaev A.A., Khabchabov R.G., Makhmudova E.R., Gafurova R.M., Islamova U.A., Anatova A.A., Dzhanbulatov M.A. Influence of discharge time after coronary artery stenting on the incidence of restenosis and exacerbations of ischemic heart disease. EMERGENCY MEDICAL CARE. 2025;26(2):70-77. (In Russ.) https://doi.org/10.24884/2072-6716-2025-26-2-70-77