Evaluation of the efficiency and safety of emergency medical care with uncontrolled arterial hypertension
https://doi.org/10.24884/2072-6716-2022-23-4-41-47
Abstract
In 91 patients with uncontrolled arterial hypertension, the efficacy and safety of combinations of antihypertensive drugs were compared. 30 patients received a combination of captopril and furosemide; 32 — moxonidine and furosemide; 29 — moxonidine and nifedipine. Drugs were prescribed by fixed randomization using a table of random numbers. It is shown that the combination of captopril and furosemide has a sufficient, but not stable antihypertensive effect, moxonidine and nifedipine, moxonidine and furosemide — a sufficient and stable effect. When using moxonidine and nifedipine, a significantly higher frequency of excessive lowering of blood pressure was detected. The proposed method of registration and evaluation of blood pressure monitoring of funds is easily feasible at the pre-hospital stage.
About the Authors
V. V. Ruksin
North-Western State Medical University I.I. Mechnikov
Russian Federation
Russian Federation
St. Petersburg
O. V. Grishin
North-Western State Medical University I.I. Mechnikov
Russian Federation
Russian Federation
St. Petersburg
V. P. Kitsyshin
Kirov Military Medical Academy
Russian Federation
Russian Federation
St. Petersburg
I. Yu. Lukyanova
North-Western State Medical University I.I. Mechnikov
Russian Federation
Russian Federation
St. Petersburg
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Review
For citations:
Ruksin V.V., Grishin O.V., Kitsyshin V.P., Lukyanova I.Yu. Evaluation of the efficiency and safety of emergency medical care with uncontrolled arterial hypertension. EMERGENCY MEDICAL CARE. 2022;23(4):41-47. (In Russ.) https://doi.org/10.24884/2072-6716-2022-23-4-41-47
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