The impact of modern inhaled anesthetics on hemodynamics and cognitive status during laparoscopic cholecystectomy

Abstract

The article presents a comparative assessment of the effect of sevoflurane and desflurane on intraoperative hemodynamic parameters and sedation level during laparoscopic cholecystectomy was carried out. A modern scheme for assessing perioperative cognitive status is presented.

The aim of the work is to conduct a comparative assessment of the effect of sevoflurane and desflurane on hemodynamic parameters during laparoscopic cholecystectomy. To study the frequency of postoperative cognitive dysfunction in the immediate postoperative period when using sevoflurane and desflurane.

Materials and methods: The study included 60 patients of both sexes operated on for cholelithiasis by laparoscopic cholecystectomy. The patients were divided into two groups of 30 people depending on the anesthetic used. In group 1, sevoflurane was used. In group 2, desflurane was used. The degree of anesthetic risk of patients was according to ASA I–II degree.

The results and their discussion. The effect of sevoflurane and desflurane in the dosages used on hemodynamic and gas exchange parameters did not differ significantly, with the exception of a significantly lower value in group 1 of ADd, ADsr, heart rate at the 2nd stage of the study and ADs after applying carboxyperitoneum at the 3rd stage. With laparoscopic interventions of medium duration, sevoflurane and desflurane do not have a negative effect on postoperative cognitive status