Modern approaches to emergency medical care for convulsive syndrome in children and adolescents: literature review
Yu. V. Bykov,
А. N. Оbedin,
О. V. Zinchenko,
I. V. Yatsuk,
E. V. Vоlkov,
V. V. Fischer,
A. A. Muravyova https://doi.org/10.24884/2072-6716-2025-26-2-78-84
Abstract
Aim. To analyze national and foreign scientific publications dedicated to aspects of treatment of seizure syndrome (SS) in children and adolescents at the prehospital stage. Materials and methods. A total of 26 international and national sources dealing with issues relevant to SS were analyzed, including 10 papers published in the last 5 years. Results. At the prehospital stage, children and adolescents with SS should undergo an objective examination, restoration of patency of the upper respiratory tract, respiratory support and stabilization of hemodynamics. The drugs of choice for the relief of SS are benzodiazepines, with the ineffectiveness of which valproic acid is used. In case of hypoglycemia, hyperthermia and cerebral edema, symptomatic drug therapy is performed. Conclusion. The analysis of the literature is of practical importance for emergency physicians in providing emergency care to children with SS at the prehospital stage.
About the Authors
Yu. V. Bykov
Stavropol State Medical University; Children’s City Clinical Hospital named after G. K. Filippsky
Russian Federation
Russian Federation
Yuri V. Bykov
Stavropol
А. N. Оbedin
Stavropol State Medical University; Regional Clinical Perinatal Center No. 1
Russian Federation
Russian Federation
Аlexander N. Оbedin
Stavropol
О. V. Zinchenko
Stavropol State Medical University
Russian Federation
Russian Federation
Оleg V. Zinchenko
Stavropol
I. V. Yatsuk
Stavropol State Medical University; City Clinical Hospital of Emergency Medical Care
Russian Federation
Russian Federation
Ivan V. Yatsuk
Stavropol
E. V. Vоlkov
Stavropol State Medical University; Regional Clinical Hospital
Russian Federation
Russian Federation
Evgeny V. Vоlkov
Stavropol
V. V. Fischer
Stavropol State Medical University; Shpakovskaya District Hospital
Russian Federation
Russian Federation
Vasiliy V. Fischer
Stavropol
Mikhailovsk
A. A. Muravyova
Stavropol State Medical University
Russian Federation
Russian Federation
Alla A. Muravyova
Stavropol
References
1. Shah M.I., Macias C.G., Dayan P.S., Weik T.S., Brown K.M., Fuchs S.M. An Evidence-based Guideline for Pediatric Prehospital Seizure Management Using GRADE Methodology // Prehosp. Emerg. Care. 2014. Vol. 18. P. 15–24.
2. Meyburg J., Bernhard M., Hoffmann G.F., Motsch J. Principles of pediatric emergency care // Dtsch Arztebl Int. 2009. Vol. 106. P. 739–747.
3. Remick K., Redgate C., Ostermayer D. Kaji A. H., Gausche-Hill M. Prehospital Glucose Testing for Children with Seizures: A Proposed Change in Management // Prehosp. Emerg. Care. 2017. Vol. 21. P. 216–221.
4. Sasidaran K., Singhi S., Singhi P. Management of acute seizure and status epilepticus in pediatric emergency // Indian J. Pediatr. 2012. Vol. 79. P. 510–517.
5. Sahin S., Yazici M. U., Ayar G., Karalok Z. S., Arhan E. P. Seizures in a Pediatric Intensive Care Unit: A Prospective Study // J. Trop. Pediatr. 2016. Vol. 62. P. 94–100.
6. Shaitor V.M. Emergency anticonvulsant therapy in children at the prehospital stage // Emergency medical care, 2019, No. 1, pp. 35–39 (In Russ.).
7. Martindale J.L., Goldstein J.N., Pallin D.J. Emergency department seizure epidemiology // Emerg. Med. Clin. North Am. 2011. Vol. 29. P. 15–27.
8. Seinfeld S., Shinnar S., Sun S. Hesdorffer D.C., Deng X., Shinnar R.C. Emergency management of febrile status epilepticus: results of the FEBSTAT study // Epilepsia. 2014. Vol. 55. P. 388–395.
9. Silverman E., Sporer K.A., Lemieux J.M., Brown J.F., Koenig K.L., Gausche-Hill M. Prehospital Care for the Adult and Pediatric Seizure Patient: Current Evidence-based Recommendations // West J. Emerg. Med. 2017. Vol. 18. P. 419–436.
10. Firnberg M.T., Lerner E.B., Nan N., Ma C.X., Shah M.I., Mann N.C. National Variation in EMS Response and Antiepileptic Medication Administration for Children with Seizures in the Prehospital Setting // West J. Emerg. Med. 2023. Vol. 24. P. 805–813.
11. Baranov A.A., Bagnenko S.F., Namazova-Baranova L. S. еt al. Federal clinical guidelines for emergency medical care for convulsions in children. 2015 (In Russ.).
12. Bykov Yu.V., Obedin A.N., Fischer V.V. еt al. Emergency care for febrile seizures. Textbook. Stavropol: SGMU, 2024. 70 p. (In Russ.).
13. Friedman J. N. Emergency management of the paediatric patient with generalized convulsive status epilepticus // Paediatr Child Health. 2011. Vol. 162. P. 91–97.
14. Crawshaw A.A., Cock H.R. Medical management of status epilepticus: Emergency room to intensive care unit // Seizure. 2020. Vol. 75. P. 145–152.
15. Shkurenkova L.P., Saida Z., Ryspanova M. Convulsive syndrome in children. Emergency care at the prehospital stage. Bulletin of the Kazakh National Medical University, 2012, No. 4, рр. 148–150 (In Russ.).
16. Al Sawaf A., Arya K., Murr N.J. Seizure Precautions. StatPearls [Internet]. 2023.
17. McKenzie K.C., Hahn C.D., Friedman J. N. Emergency management of the paediatric patient with convulsive status epilepticus // Paediatr Child Health. 2021. Vol. 26. P. 50–66.
18. Aulická S. Current Management of Generalized Convulsive Status Epilepticus in Children // Children (Basel). 2022. Vol. 9. P. 1586.
19. Bykov Yu.V., Obidin A.N., Fischer V.V. еt al. Febrile seizures in pediatric practice: risk factors, clinical manifestations, intensive care. Ural Medical Journal, 2023, No. 6, рр. 113–123 (In Russ.).
20. Yoong M., Chin R.F., Scott R.C. Management of convulsive status epilepticus in children // Arch. Dis. Child Educ. Pract. Ed. 2009. Vol. 94. P. 1–9.
21. Claassen J., Silbergleit R., Weingart S. D. et al. Emergency neurological life support: status epilepticus // Neurocrit Care. 2012. Vol. 17. P. 73–78.
22. Mechem C.C., Barger J., Shofer F.S. Short-term outcome of seizure patients who refuse transport after out-ofhospital evaluation // Acad. Emerg. Med. 2001. Vol. 8. P. 231–236.
23. Chin R.F., Neville B.G., Peckham C. Treatment of community-onset, childhood convulsive status epilepticus: A prospective, population-based study // Lancet Neurol. 2008. Vol. 8. P. 696–703.
24. Laino D., Mencaroni E., Esposito S. Management of Pediatric Febrile Seizures // Int. J. Environ. Res. Public Health. 2018. Vol. 15. P. 2232.
25. Beskind D.L., Rhodes S.M., Stolz U., Birrer B., Mayfield T.R., Bourn S. When should you test for and treat hypoglycemia in prehospital seizure ients? // Prehosp Emerg Care. 2014. Vol. 18. P. 433–441.
26. Tiwari A., Meshram R.J., Singh R.K. Febrile Seizures in Children: A Review // Cureus. 2022. Vol. 14. P. 31509.
Review
For citations:
Bykov Yu.V., Оbedin А.N., Zinchenko О.V., Yatsuk I.V., Vоlkov E.V., Fischer V.V., Muravyova A.A. Modern approaches to emergency medical care for convulsive syndrome in children and adolescents: literature review. EMERGENCY MEDICAL CARE. 2025;26(2):78-84. (In Russ.) https://doi.org/10.24884/2072-6716-2025-26-2-78-84
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